Metastable Crystallization by Drop Impact
نویسندگان
چکیده
It has been reported that cavitation bubbles (air–liquid interface) by femtosecond laser and ultrasonic irradiations are effective for metastable phase crystallization in polymorph control. also noted generated mechanical shock when dropping a vial. Here we describe the of acetaminophen drop impact. In condition where spontaneous nucleation did not occur, impact produced form (form II) trihydrate. This supports potency air–liquid interface formation. Furthermore, is completely new phenomenon, developments expected future.
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ژورنال
عنوان ژورنال: Crystals
سال: 2022
ISSN: ['2073-4352']
DOI: https://doi.org/10.3390/cryst12081104